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Ng et al., Journal of Endocrinology observed targeted reductions in fat deposits without adverse metabolic effects

control group: n = 324) demonstrated the largest effect size (SMD = 0.75

R.HetzC.RenJ

While any oxidation of the GSH is to be avoided, the GSSG has less toxicity than ROS-products of GSH, and indeed GSSG is known to be absorbed and available for hepatic reduction to GSH, though at the cost of increased metabolic load with respect to GSH administration